Why here: It's the ultimate mix of city and sea, with wide white sands, warm turquoise waters, and pastel art-deco buildings everywhere you look. As for the hotels of South Beach, this is where the pool-scene-as-fashion-show was born.
See and do: Practically every resident has a hot bod and deep tan. Be like local Enrique Iglesias and rent Jet Skis, or be more Khloé and Kourtney and jog it out; the two-mile boardwalk has sweeping ocean views. Head to the Design District, an industrial-chic neighborhood with boutiques (Prada, Louis Vuitton) and art galleries (Adamar, Etra), for a culture fix. Then check out Top Chef alum Jeff McInnis's Yardbird for creative, hearty southern fare like sweet-tea-brined ribs with pickled chilies.
Stay: To design the SLS Hotel South Beach, Philippe Starck channeled Madame de Pompadour, Louis XV's mistress, with mirrors on the ceiling and black-and-white tapestries. If excess rules at SLS, then the nearby Townhouse hotel, with its white-plus-splashes-of-red interiors, is a cool case study in minimalism. From $325; SLS Hotel South Beach. From $115; Townhouse hotel.