Morning Touch down in Cancún; from there it's a 90-minute cab ride south to Tulum. People walk or bike to and from their hotels—Iguana Bike Shop will deliver a pair to you; 52-984-119-0836. You can rent a car by the day for excursions, and taxis are a good option after cocktails.
Afternoon Check into Coqui Coqui, a seven-suite limestone beach retreat run by the poster couple for Tulum's fashion scene: accessories designer Francesca Bonato and her partner, model and perfumer Nicolas Malleville. Expect to see a few famous faces (Daria Werbowy, Kate Bosworth) mixed in with regular cool and creative types. (Get Francesca's tips on what to pack for Tulum here.) Rooms from $270.
Evening Grab dinner at one of the five tables, for guests only—be sure to order the consistently delicious catch of the day.
Morning Toss towels in your bag and bike or walk to the nearby Tulum ruins: Mayan mini-pyramids overlooking the Caribbean Sea. You can't avoid the tourists, but head down to the beach; you won't believe the incredible pale blue shade of the water.
Afternoon Tequila fish tacos are fantastic with the high-octane margaritas at ¡Que Fresco!, a casual bistro on the sand where everyone swims in between courses.
Evening Break out your best dress (or maybe your craziest caftan) for Casa Jaguar, a stylish fusion restaurant beloved by Nicola Formichetti, Lady Gaga's stylist; 52-984-155-2328.
Morning By kayak, explore the Sian Ka'an Biosphere, a 1.6 million-acre nature reserve filled with mangrove islands and lagoons.
Afternoon Indulge in a coconut-oil massage and Mayan clay facial at Coqui Coqui's tiny (but exquisite) rooftop spa.
Evening At foodie hangout Hechizo, begin with the truffle fettuccine and end with a chocolate torte.
Morning Move to the sleek 20-suite Be Tulum, definitely the area's most upscale resort. There's air-conditioning, for one (a rarity in these parts), and ground-floor rooms come with private plunge pools. Rooms from $403.
Afternoon Rent snorkel gear at Gran Cenote, a huge cave-and-river system, and drift in the cool waters.
Evening Knock back a few Don Pepinos (Mexican cucumber, fresh basil, and tequila) at Be Tulum before heading into town to split a crispy pizza at La Nave; 52-984-871-2592.
Morning Hatha, ashtanga, anusara: Pick your yoga method, and join a class at Maya Tulum, a world-class wellness retreat.
Afternoon The Viceroy Riviera Maya is in Playa del Carmen, 45 minutes north (about a $50 taxi ride, one way), but the holistic spa is worth the detour; have the resident shaman bless you before your massage. And if you'd rather make Playa your base, this adults-only haven is also famous for its 41 rustic-chic villas and superb staff. Rooms from $600.
Evening Molecular gastronomy has made it to the Riviera Maya by way of Passion, the restaurant of Michelin-star chef Martin Berasategui at the new Paradisus Playa del Carmen La Perla. (It's close to the Viceroy.) If you're looking for all-inclusive, this resort is truly luxurious, with design-focused rooms and butler service. Rooms from $460.
Morning Rent bikes at the less touristy Coba archaeological site (it s about one hour from Tulum), and pedal your way through the lush jungle.
Afternoon Body-surf at Be Tulum, catch up on reading, and remember why you married this guy in the first place.
Evening At the beachfront Posada Margherita, it's all about the pasta, made fresh every day. The people-watching is a close second.
Morning Pick up buttery croissants from La Fournée Panaderia & Pasterliera, an authentic French bakery.
Afternoon On your way to the airport, stop for lunch at the posh Maroma, halfway between Tulum and Cancún. This hacienda-style resort sits on one of the area's widest, most pristine beaches. You might end up staying an extra night. Rooms from $765.